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Factors such as the form of B12 used, additional ingredients, and manufacturing standards should be considered

The term impaired sensitivity to B12 more aptly captures this condition than functional B12 deficiency, encompassing a broader portrayal of the potential underlying pathological physiological process involving decreased responsiveness to B12 treatment, including B12 absorption, transport, intracellular metabolism, and mitochondrial MMA metabolism

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Retrieved 16 February 2017

It plays a key role in fertility treatments